Chemotherapy platinum agents
WebChemotherapy is the use of drugs to destroy cancer cells. This type of cancer treatment works by keeping cancer cells from growing, dividing, and making more cells. Chemotherapy can be used as a treatment for many different cancers. Your doctor may refer to chemotherapy as standard chemotherapy, traditional chemotherapy, or …
Chemotherapy platinum agents
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WebMay 29, 2014 · Abstract. The platinum-based drugs cisplatin, carboplatin, and oxaliplatin belong to the most widely used chemotherapeutics in oncology, showing clinical efficacy against many solid tumors. Their main mechanism of action is believed to be the induction of cancer cell apoptosis as a response to their covalent binding to DNA. In recent years, … WebChemotherapy for Breast Cancer. Chemotherapy (chemo) uses anti-cancer drugs that may be given intravenously (injected into your vein) or by mouth. The drugs travel through the bloodstream to reach cancer cells in most parts of the body. Sometimes, if cancer spreads to the spinal fluid, which surrounds and cushions the brain and spinal cord ...
The first platinum-based chemotherapy drug, cisplatin, was approved for use by the FDA in 1978Trusted Source. Researchers are continuing to examine newer drugs that may cause fewer side effects. See more Platinum-based chemotherapy drugs can cause serious complications, such as cognitive changes or cardiovascular problems. Your doctor may recommend lowering your dose or stopping treatment if you develop severe … See more Researchers are continuing to examine whether platinum-based chemotherapy is safe for people who are pregnant or breastfeeding. In a small 2024 study, researchers found evidence that it might be reasonably safe … See more According to the American Cancer SocietyTrusted Source, it’s generally not recommended to receive a vaccine during chemotherapy or radiation treatment. The exception is the flu … See more A dose-limiting side effect is a side effect that’s serious enough to prevent doctors from increasing the dose of the drug further. The dose-limiting side effect of cisplatin is nephrotoxicity, the deterioration of your kidney … See more WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, ... Some chemo drugs may have long-term or even permanent side effects: Cisplatin can cause kidney damage. To help prevent this, doctors give lots of IV fluid before and after this ...
WebAug 21, 2024 · At present, the first-line chemo for OC is on the basis of the combined use of platinum-derived cytotoxic agents and paclitaxel. Despite high response rate and median PFS, over 70% of these patients would finally suffer disease progression. The emergency of resistance to platinum-resistant chemo mainly accounts for the deaths with recurrent OC. WebHence, Pt drugs may still be part of the standard of care for several cancers in the coming years. Platinum chemotherapy agents remain among the most widely used anticancer drugs, but there is ...
Webplatinum-based chemotherapy. However, the toxicity of che-motherapy influences further therapy and even survival time. We concluded that polymorphisms of CASP8 contribute to the prognosis of advanced lung adenocarcinoma patients treated with platinum-based chemotherapy. And we think polymorphisms of CASP8 may be …
WebPlatinum drugs combined with other agents have been the first-line treatment for non-small cell lung cancer (NSCLC) in the past decades. To better evaluate the efficacy of platinum–based chemotherapy in NSCLC, we establish a platinum chemotherapy response prediction model. Here, a total of 217 samples from Xiangya Hospital of … if delta h is positiveWebPlatinum drugs are important components of multiagent chemotherapy regimens for numerous malignancies, including sarcomas, and tumors of the testes, ovary, bladder, lung, brain, head and neck, and others (Kelland, 2007). Cisplatin is known to produce … is smart meter api open sourceWebPlatinum-based chemotherapy agents including carboplatin (Paraplatin®), cisplatin (Platinol®), and oxaliplatin (Eloxatin®), are used for the treatment of various cancer types. Platinum chemotherapy is not FDA approved for the treatment of prostate cancer; however, it is sometimes used in very advanced prostate cancer patients who have ... if demand is high what happens to priceWebApr 11, 2024 · Compared with using chemotherapy alone, anti-angiogenic agents, targeted therapy, and immunotherapy can provide more benefits in survival rate for recurrent platinum resistance. Although various anti-cancer agents are used in treating recurrent platinum-resistant ovarian cancer, there is no consensus on the international standards … ifdescr ifnameWebDec 21, 2024 · Platinum (Pt) agents, usually referring to carboplatin (Cb) and cisplatin(DDP), are cytotoxic DNA-damaging chemo-drugs widely used in various malignancies. Platinum can cause DNA strand breaks ... if demand is perfectly inelasticWebThe platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events). In total, a cancer … is smart mouth mouthwash safe to useWebAlkylating agents are compounds that work by adding an alkyl group to the guanine base of the DNA molecule, preventing the strands of the double helix from linking as they should. ... Note: Although the platinum-containing anticancer agents, carboplatin, cisplatin, and oxaliplatin are frequently classified as alkylating agents, they are not ... if devin is purhcasing a 1500 sterroe