Cytotoxicity and antiproliferative
WebJan 19, 2024 · L. pedunculata EO presented the most pronounced cytotoxic/antiproliferative activity against tumor cells, with moderate cytotoxicity against non-tumor cells. Whereas, M. cervina EO exhibited a slightly lower cytotoxic effect against tumor cells and did not affect the viability of non-tumor cells. WebMay 1, 2024 · Antiproliferative effect of the most active compounds was also tested through Sulforhodamine B (SRB) assay. Briefly, cells were seeded to a final density of 2500 cells/well in 96-well tissue culture plates and incubated in …
Cytotoxicity and antiproliferative
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WebMay 21, 2024 · The photoirritancy factor of the compounds was calculated. Using the MTT test, the antiproliferative activity to MCF-10A, MCF-7 and MDA-MB-231 cell lines was … WebCytotoxicity and antiproliferative activity are two terms that are used to describe the ability of an agent to kill cells. Cytotoxicity refers to the agent’s ability to kill cells, and …
WebCisplatin and its derivatives are the main metallodrugs used in cancer therapy. However, low selectivity, toxicity and drug resistance are associated with their use. The zinc(II) … WebSep 17, 2013 · The antiproliferative activity of the apigenin derivatives was evaluated by an MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay. We determined that 4a–4j displayed better growth inhibition activity against four human cancer cell lines, namely, human lung (A549), human cervical (HeLa), human hepatocellular liver (HepG2 ...
WebMaterials and methods: Bioassay-guided cytotoxicity fractionations using the Hep-2 cell line of the hexane extracts from these brown algae were analyzed using various … WebApr 5, 2024 · In addition, in vitro cytotoxicity against the HepG2 cell line showed significant anticancer activity, and approximately 100 μg/mL is required to decrease viability compared with that of the control. ... Several therapeutic uses of C. gileadensis have been reported and include the antiproliferative properties of the ethanolic extract of C ...
WebDec 20, 2024 · According to Choi, et al., AgNPs develop a potential cytotoxic effect on A2780 ovarian carcinoma cells and ovarian cancer stem cells (OvCSCs) at high …
WebOct 8, 2015 · Although the specific mechanisms causing the reduced cell viability and cytotoxicity after the treatment with crude secretion are still unknown, it may be … cif de inglaterraWebMar 13, 2024 · The water and methanolic extracts from Spirulina exhibited dose-dependent cytotoxicity against HepG2 cells with IC 50 of 1.7 ± 0.14 and 1.28 ± 0.22 mg/ml, respectively. Similarly, Wu et al. [ 28 ] reported that the water extracts of Spirulina and Chlorella have potent antiproliferative effects on HSC and HepG2 cells. cif de wallboxWebCytotoxicity of TiO 2 MBs, TiO 2 + 5%Gd MBs, and TiO 2 + 10%Gd MBs was evaluated using the resazurin assay that measures the mitochondrial activity of cells. The mitochondrial activity of MG-63 was unaffected by the treatment with all used MBs (Fig. 4).Our results show that all the used MBs are noncytotoxic, an important requirement for … dharma beach clubWebAntiproliferative activity of APs and APCs were evaluated using various animal studies. Gossé et al. 26 reported the inhibitory effects of APCs in a model of colon cancer induced by intraperitoneal injections of azoxymethane; ... The cytotoxicity of compound 1 was also reported against ovarian carcinoma A2780 cells ... cif diagonal company services \\u0026 solutions slWebMar 1, 2024 · Quinizarin (compound 4) had moderate cytotoxicity against RAW 264.7 cells with LC50 value of 21.59 μg/ml and SI of 3.26. Rossi et al. (2010) previously reported the antiproliferative potential of quinizarin on B16-F10 melanoma murine cells, In addition, several data demonstrate the promising action of anthraquinones as anticancer agents ... cif de lowiWebIn almost all cases, growth inhibition by the flavonoids occured in the absence of cytotoxicity. There was no obvious structure-activity relationship in the antiproliferative effects either on basis of the subclasses (i.e., isoflavones, flavones, flavonols, flavanones) or with respect to kind or position of substituents within a class. cif de wixWebThe outcome of the brine shrimp lethality test showed that ethyl acetate and water fraction cytotoxicity were more than 1000 ppm and 337.07 ppm, respectively, at a lethal concentration of 50. Antiproliferative activity analyses were performed using direct hemocytometer counting. dharma blockchain